GMP Human TNF-alpha Protein

Catalog number GMP-TNAH23-500ug

Discontinued

Price for GMP-TNAH23-500ug

Size / count 500 µg

This variant is discontinued and cannot be added to your cart.

About this product

GMP Human TNF-alpha Protein (GMP-TNAH23) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # P01375).

Specifications

Catalog number: GMP-TNAH23-500ug
Size / count: 500 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Specifications: This protein carries no "tag". The protein has a calculated MW of 17.4 kDa. The protein migrates as 17 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Val 77 - Leu 233
Host: HEK 293
Target: TNF-alpha
Conjugation: Unconjugated
Tag: Native
Source: Human
Stability: -20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution._x000D_ Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin: 10 EU/mg
Purity: 95%
Format: Powder-GMP
Buffer: PBS, pH7.4
Molecular Weight: 17.4 kDa
Shipping Conditions: Blue ice
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for GMP Human TNF-alpha Protein?

The catalog number for GMP Human TNF-alpha Protein is GMP-TNAH23-500ug.

Is GMP Human TNF-alpha Protein in stock?

GMP Human TNF-alpha Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GMP Human TNF-alpha Protein?

GMP Human TNF-alpha Protein is manufactured by CRB.

What is the estimated delivery time for GMP Human TNF-alpha Protein?

Estimated delivery time for GMP Human TNF-alpha Protein is approximately 10 business day(s), depending on your location.

What is GMP Human TNF-alpha Protein used for?

GMP Human TNF-alpha Protein (GMP-TNAH23) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # P01375).

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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