GMP Human IFN-gamma Protein

Catalog number GMP-IFGH24-500ug

Discontinued

Price for GMP-IFGH24-500ug

Size / count 500 µg

This variant is discontinued and cannot be added to your cart.

About this product

GMP Human IFN-gamma Protein (GMP-IFGH24) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Gln 166 (Accession # P01579).

Specifications

Catalog number: GMP-IFGH24-500ug
Size / count: 500 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.
Specifications: This protein carries no "tag". The protein has a calculated MW of 16.8 kDa. The protein migrates as 15 kDa, 19 kDa and 24 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Gln 24 - Gln 166
Host: HEK 293
Target: IFN-gamma
Conjugation: Unconjugated
Tag: Native
Source: Human
Stability: -20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution._x000D_ Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin: 10 EU/mg
Purity: 95%
Format: Powder-GMP
Buffer: PBS, pH7.4
Molecular Weight: 16.8 kDa
Shipping Conditions: Blue ice
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for GMP Human IFN-gamma Protein?

The catalog number for GMP Human IFN-gamma Protein is GMP-IFGH24-500ug.

Is GMP Human IFN-gamma Protein in stock?

GMP Human IFN-gamma Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GMP Human IFN-gamma Protein?

GMP Human IFN-gamma Protein is manufactured by CRB.

What is the estimated delivery time for GMP Human IFN-gamma Protein?

Estimated delivery time for GMP Human IFN-gamma Protein is approximately 10 business day(s), depending on your location.

What is GMP Human IFN-gamma Protein used for?

GMP Human IFN-gamma Protein (GMP-IFGH24) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Gln 166 (Accession # P01579).

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.