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Product details

Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified)

Catalog number SPD-C82Ex-25ug

Discontinued

Price for SPD-C82Ex-25ug

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Size / count 25 µg

This variant is discontinued and cannot be added to your cart.

About this product

Biotinylated SARS-CoV-2 Spike RBD, His,Avitag (BA.2.12.1/Omicron) (SPD-C82Ex) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.12.1; GISAID clade: GRA).

Specifications

Catalog number
SPD-C82Ex-25ug
Size / count
25 µg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Specifications
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 28.4 kDa. The protein migrates as 34-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region
Arg 319 - Lys 537
Host
HEK 293
Target
Spike RBD
Conjugation
Biotin-labeled
Tag
C-10×His & C-Avi
Source
SARS-CoV-2
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 5 μg/mL (100 μL/well) can bind Biotinylated SARS-CoV-2 Spike RBD, His,Avitag (BA.2.12.1/Omicron) (Cat. No. SPD-C82Ex) with a linear range of 1-63 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
28.4 kDa
Shipping Conditions
Room Temperature
Storage Conditions
-20°C

Frequently Asked Questions

What is the catalog number for Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified)?

The catalog number for Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) is SPD-C82Ex-25ug.

Is Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) in stock?

Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified)?

Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) is manufactured by CRB.

What is the estimated delivery time for Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified)?

Estimated delivery time for Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) is approximately 10 business day(s), depending on your location.

What is Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.12.1/Omicron) (MALS verified) used for?

Biotinylated SARS-CoV-2 Spike RBD, His,Avitag (BA.2.12.1/Omicron) (SPD-C82Ex) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)).

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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