PE-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45) (Site-specific conjugation) (Preservative free)

About this product

PE-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (FM3-HPY53) is a neutralizing antibody produced via site-specific conjugation of PE to Monoclonal Anti-FMC63 Antibody, Mouse IgG1 under optimal conditions with a proprietary technology. We also carry another proclin-containing version of PE-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (FM3-PY54A2) produced with the same production process except for proclin, and the proclin-containing product has the same performance and can be stored under 2-8 °C for no less than 12 months after reconstitution.

Specifications

Catalog number

FM3-HPY53-200tests

Size / count

200 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Background

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

CAS Number

9007-83-4

Host

HEK293

Origin Species

Mouse

Target

FMC63

Conjugation

PE Labeled

Tag

Mouse IgG1 | Mouse Kappa

Applications

Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) . Please note that this product is NOT compatible to streptavidin detection system.

Stability

-20°C to -70°C for 24 months in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.

Format

Powder

Buffer

PBS, 0.5% BSA, pH7.4

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C, avoid light

Package Size

200tests*1

Host or Source

HEK293

Species

Mouse

Preservative

Trehalose