Rat CD3 epsilon&CD3 delta Heterodimer Protein, Llama Fc Tag&Llama Fc Tag (MALS verified)

About this product

Rat CD3E&CD3D Heterodimer Protein, Llama Fc Tag&Llama Fc Tag (CDD-R5257) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Asp 103 (CD3E) & Phe 22 - Gly 106 (CD3D) (Accession # D4A5M2-1 (CD3E) & P19377-1 (CD3D)).

Specifications

Catalog number

CDD-R5257-1mg

Size / count

1 mg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Specifications

Rat CD3E&CD3D Heterodimer Protein, Llama Fc Tag&Llama Fc Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 40.8 kDa (CD3E) and 40.9 kDa (CD3D). Subunit CD3E is fused with a llama IgG2b Fc tag at the C-terminus and subunit CD3D is fused with a llama IgG2b Fc tag at the C-terminus. The reducing (R) protein migrates as 55-60 kDa due to glycosylation.

Expression Region

Gln 21 - Asp 103 (CD3E) & Phe 22 - Gly 106 (CD3D)

Host

HEK 293

Target

CD3E & CD3D

Conjugation

Unconjugated

Tag

C-LlamaFc(LlamaIgG2b) | C-LlamaFc(LlamaIgG2b)

Source

Rat

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

40.8 kDa (CD3E) & 40.9 kDa (CD3D)

Shipping Conditions

Room Temperature

Storage Conditions

-20°C