Anti-PU.1/Spi1 Antibody (Biotine Conjugate) — image 1 of 2

Product details

Anti-PU.1/Spi1 Antibody (Biotine Conjugate)

Catalog number RP1097-Biotin

Price for RP1097-Biotin

Size / count 100 µg/Vial

About this product

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: RP1097-Biotin
Size / count: 100 µg/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Transcription factor PU.1;31 kDa-transforming protein;SPI1;
Gene Name: Transcription factor PU.1
UniProt: P17947
Host: Rabbit
Reactivity: Human,Mouse,Rat
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: E.coli-derived human PU.1/Spi1 recombinant protein (Position: E18-K196). Human PU.1/Spi1 shares 84% and 84.4% amino acid (aa) sequence identity with mouse and rat PU.1/Spi1, respectively.
Clonality: Polyclonal
Applications: IHC
Purification: Immunogen affinity purified.
Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function: Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity). .
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Applications Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat <br>
Subcellular Location: Nucleus .
Protein Name: Transcription factor PU.1

Frequently Asked Questions

What is the catalog number for Anti-PU.1/Spi1 Antibody (Biotine Conjugate)?

The catalog number for Anti-PU.1/Spi1 Antibody (Biotine Conjugate) is RP1097-Biotin.

What sizes are available for Anti-PU.1/Spi1 Antibody (Biotine Conjugate)?

Anti-PU.1/Spi1 Antibody (Biotine Conjugate) is available in the following size(s): 100 µg/Vial.

Is Anti-PU.1/Spi1 Antibody (Biotine Conjugate) in stock?

Anti-PU.1/Spi1 Antibody (Biotine Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PU.1/Spi1 Antibody (Biotine Conjugate)?

The safety data sheet for Anti-PU.1/Spi1 Antibody (Biotine Conjugate) is available here: https://www.bosterbio.com/msds?sku=RP1097.

What is Anti-PU.1/Spi1 Antibody (Biotine Conjugate) used for?

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.