Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) — image 1 of 3

Product details

Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate)

Catalog number RP1034-Dylight488

Discontinued

Price for RP1034-Dylight488

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody catalog # RP1034. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: RP1034-Dylight488
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.
Synonyms: Multidrug resistance protein 1;3.6.3.44;ATP-binding cassette sub-family B member 1;P-glycoprotein 1;CD243;ABCB1;MDR1, PGY1;
Gene Name: Multidrug resistance protein 1
UniProt: P08183
Host: Rabbit
Reactivity: Human,Mouse,Rat
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human P Glycoprotein, different from the related rat sequence by twelve amino acids.
Clonality: Polyclonal
Tissue Specificity: Expressed in liver, kidney, small intestine and brain.
Applications: IHC
Purification: Immunogen affinity purified.
Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Applications Notes: Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Mouse, Rat, -<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat<br>
Subcellular Location: Cell membrane ; Multi-pass membrane protein .
Sequence Similarities: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Protein Name: Multidrug resistance protein 1

Frequently Asked Questions

What is the catalog number for Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate)?

The catalog number for Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) is RP1034-Dylight488.

Is Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) in stock?

Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate)?

The safety data sheet for Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) is available here: https://www.bosterbio.com/msds?sku=RP1034.

What is Anti-P Glycoprotein/ABCB1 Antibody (Dylight488 Conjugate) used for?

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody catalog # RP1034. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.