Anti-Interleukin-13 IL13 Antibody (Dylight488 Conjugate)

About this product

Boster Bio Anti-Interleukin-13 IL13 Antibody catalog # RP1048. Tested in ELISA applications. This antibody reacts with Rat.

Specifications

Catalog number

RP1048-Dylight488

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Synonyms

Interleukin-13;IL-13;T-cell activation protein P600;Il13;Il-13;

Gene Name

Interleukin-13

UniProt

P42203

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E. coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL-13, respectively.

Clonality

Polyclonal

Tissue Specificity

Activated T-cells, mast cells, natural killer cells.

Applications

ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

ELISA(Cap), 0.1-0.5μg/ml, Rat<br>

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the IL-4/IL-13 family.

Protein Name

Interleukin-13