Anti-Peptide YY/PYY Antibody (Dylight488 Conjugate)

About this product

Boster Bio Anti-Peptide YY/PYY Antibody Picoband® catalog # PB10014. Tested in IF, IHC applications. This antibody reacts with Mouse, Rat.

Specifications

Catalog number

PB10014-Dylight488

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a peptide that in humans is encoded by the PYY gene. This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. <p>Ready to elevate your research? Embrace the freedom to customize your peptides based on sequence, purity, and modifications. We're here to support your scientific endeavors with our top-notch <a href="https://www.bosterbio.com/services/custom-peptide-synthesis" style="color:#ea8d28">custom peptide synthesis</a> service.</p>

Synonyms

Peptide YY ;PYY ;Peptide tyrosine tyrosine;Peptide YY (3-36) ;PYY-II ;Pyy;

Gene Name

Peptide YY

UniProt

Q9EPS2

Host

Rabbit

Reactivity

Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of mouse Peptide YY, different from the related human sequence by three amino acids, and identical to the related rat sequence.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. .

Applications

IF,IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat<br> Immunofluorescence, 5 μg/ml, Rat<br>

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Protein Name

Peptide YY