Anti-Glucose Transporter 5 GLUT5/SLC2A5 Antibody Picoband® (Dylight488 Conjugate)

About this product

Boster Bio Anti-Glucose Transporter 5 GLUT5/SLC2A5 Antibody catalog # PA2064. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA2064-Dylight488

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

SLC2A5, also known as GLUT5 (Glucose transporter 5), is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. In humans the GLUT5 protein is encoded by the SLC2A5 gene.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 5;Fructose transporter;Glucose transporter type 5, small intestine;GLUT-5;SLC2A5;GLUT5;

Gene Name

Solute carrier family 2, facilitated glucose transporter member 5

UniProt

P22732

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A5.

Clonality

Polyclonal

Tissue Specificity

Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Apical cell membrane ; Multi- pass membrane protein . Membrane; Multi-pass membrane protein. Localized on the apical membrane of the small intestine and the proximal tubule of the kidney. .

Sequence Similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Protein Name

Solute carrier family 2, facilitated glucose transporter member 5