Anti-Vesicular Acetylcholine Transporter/SLC18A3 Antibody Picoband® (Dylight550 Conjugate)

About this product

Boster Bio Anti-Vesicular Acetylcholine Transporter/SLC18A3 Antibody Picoband® catalog # A04891. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04891-Dylight550

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

The Vesicular acetylcholine transporter (VAChT), also known as SLC18A3, is a neurotransmitter transporter which is responsible for loadingacetylcholine (ACh) into secretory organelles in neurons making acetylcholine available for secretion. It is encoded by Solute carrier family 18, member 3 (SLC18A3) gene. This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Synonyms

Vesicular acetylcholine transporter;VAChT;Solute carrier family 18 member 3;SLC18A3;VACHT;

Gene Name

Vesicular acetylcholine transporter

UniProt

Q16572

Host

Rabbit

Reactivity

Human,Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human SLC18A3, different from the related mouse and rat sequences by five amino acids.

Clonality

Polyclonal

Tissue Specificity

Peripheral and central cholinergic nervous systems. .

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Involved in acetylcholine transport into synaptic vesicles. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Mouse<br>

Subcellular Location

Membrane ; Multi-pass membrane protein .

Protein Name

Vesicular acetylcholine transporter