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Product details

Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate)

Catalog number A00049-1-Dylight550

Discontinued

Price for A00049-1-Dylight550

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Size / count 100 µg

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About this product

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody Picoband® catalog # A00049-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number
A00049-1-Dylight550
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.
Synonyms
Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD243; ABCB1; MDR1; PGY1
Gene Name
ATP-binding cassette, sub-family B (MDR/TAP), member 1
UniProt
P08183
Host
Rabbit
Reactivity
Human,Mouse,Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human P Glycoprotein, which shares 62.9% amino acid (aa) sequence identity with rat P Glycoprotein.
Clonality
Polyclonal
Tissue Specificity
Expressed in liver, kidney, small intestine and brain.
Applications
Flow Cytometry,IF,ICC,WB
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Lyophilized
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Storage Conditions
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Applications Notes
Western blot, 0.1-0.5μg/ml<br> Immunocytochemistry/Immunofluorescence, 2μg/ml<br> Flow Cytometry (Fixed), 1-3μg/1x10<sup>6</sup> cells
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Name
Vascular endothelial growth factor A

Frequently Asked Questions

What is the catalog number for Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate)?

The catalog number for Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate) is A00049-1-Dylight550.

Is Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate) in stock?

Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate)?

The safety data sheet for Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate) is available here: https://www.bosterbio.com/msds?sku=A00049-1.

What is Anti-P Glycoprotein/ABCB1 Antibody Picoband® (Dylight550 Conjugate) used for?

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody Picoband&reg; catalog # A00049-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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