Anti-RTL3 Antibody Picoband®, Dylight550 Conjugate

About this product

Boster Bio Anti-RTL3 Antibody Picoband® catalog # A31819. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A31819-Dylight550

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Retrotransposon Gag like 3 is a protein that in humans is encoded by the RTL3 gene. This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

retrotransposon Gag like 10

Gene ID

203430

UniProt

Q8N8U3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RTL3 recombinant protein (Position: Q168-Q475).

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Jürgen Brandt, Schrauth, S. , Veith, A. M. , Froschauer, A. , Haneke, T. , & Schultheis, C. , et al. (2005). Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene, 345(1), 101-111. 2. Brandt, J. , Veith, A. M. , & Volff, J. N. . (2005). A family of neofunctionalized ty3/gypsy retrotransposon genes in mammalian genomes. Cytogenetic & Genome Research, 110(1-4), 307-317. 3. Ota, T. , Suzuki, Y. , Nishikawa, T. , Otsuki, T. , & Sugano, S. . (2004). Complete sequencing and characterization of 21,243 full-length human cdnas. Nature Genetics, 36(1), 40-45.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

14377 MW

Observed Molecular Weight

50 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1