Anti-SCNM1 Antibody Picoband®, Dylight550 Conjugate

About this product

Boster Bio Anti-SCNM1 Antibody Picoband® catalog # A10999-1. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A10999-1-Dylight550

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

SCNM1 is a zinc finger protein and putative splicing factor. In mice, Scnm1 modifies phenotypic expression of Scn8a (MIM 600702) mutations.

Gene Name

SCNM1

Gene ID

79005

UniProt

Q9BWG6

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

E.coli-derived human SCNM1 recombinant protein (Position: D8-D230). Human SCNM1 shares 82.1% amino acid (aa) sequence identity with mouse SCNM1.

Clonality

Polyclonal

Applications

WB,IHC,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Buchner, D. A., Trudeau, M., Meisler, M. H. SCNM1, a putative RNA splicing factor that modifies disease severity in mice. Science 301: 967-969, 2003. 2. Howell, V. M., Jones, J. M., Bergren, S. K., Li, L., Billi, A. C., Avenarius, M. R., Meisler, M. H. Evidence for a direct role of the disease modifier SCNM1 in splicing. Hum. Molec. Genet. 16: 2506-2516, 2007. 3. Iturrate, A., Rivera-Barahona, A., Flores, C. L., Otaify, G. A., Elhossini, R., Perez-Sanz, M. L., Nevado, J., Tenorio-Castano, J., Trivino, J. C., Garcia-Gonzalo, F. R., Piceci-Sparascio, F., De Luca, A., Martinez, L., Kalayci, T., Lapunzina, P., Altunoglu, U., Aglan, M., Abdalla, E., Ruiz-Perez, V. L. Mutations in SCNM1 cause orofaciodigital syndrome due to minor intron splicing defects affecting primary cilia. Am. J. Hum. Genet. 109: 1828-1849, 2022.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5 μg/ml, Human, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>