Anti-Fatty Acid Binding Protein 5/FABP5 Antibody Picoband®, Dylight550 Conjugate

About this product

Boster Bio Anti-Fatty Acid Binding Protein 5/FABP5 Antibody catalog # PA1475. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA1475-Dylight550

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

FABP5, Fatty acid-binding protein, epidermal, is a protein that in humans is encoded by the FABP5 gene. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. It is mapped to 8q21.13. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is though that FABPs roles include fatty acid uptake, transport, and metabolism.

Synonyms

Fatty acid-binding protein, epidermal;Epidermal-type fatty acid-binding protein;E-FABP;Fatty acid-binding protein 5;Psoriasis-associated fatty acid-binding protein homolog;PA-FABP;FABP5;

Gene Name

Fatty acid-binding protein, epidermal

UniProt

Q01469

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Fatty Acid Binding Protein 5.

Clonality

Polyclonal

Tissue Specificity

Keratinocytes; highly expressed in psoriatic skin.

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

References & Citations

1. Hertzel, A. V., Bernlohr, D. A.Cloning and chromosomal location of the murine keratinocyte lipid-binding protein gene.Gene 221: 235-243, 1998. 2. Siegenthaler, G., Hotz, R., Chatellard-Gruaz, D., Didierjean, L., Hellman, U., Saurat, J. H.Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro.Biochem J. 302: 363-371, 1994.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

15164 MW

Observed Molecular Weight

15 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat<br>Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Cytoplasm.

Sequence Similarities

Belongs to the IAP family.

Protein Name

Fatty acid-binding protein, epidermal