Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) — image 1 of 2

Product details

Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate)

Catalog number RP1097-Dylight594

Discontinued

Price for RP1097-Dylight594

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: RP1097-Dylight594
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Transcription factor PU.1;31 kDa-transforming protein;SPI1;
Gene Name: Transcription factor PU.1
UniProt: P17947
Host: Rabbit
Reactivity: Human,Mouse,Rat
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: E.coli-derived human PU.1/Spi1 recombinant protein (Position: E18-K196). Human PU.1/Spi1 shares 84% and 84.4% amino acid (aa) sequence identity with mouse and rat PU.1/Spi1, respectively.
Clonality: Polyclonal
Applications: IHC
Purification: Immunogen affinity purified.
Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function: Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity). .
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Applications Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat <br>
Subcellular Location: Nucleus .
Protein Name: Transcription factor PU.1

Frequently Asked Questions

What is the catalog number for Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate)?

The catalog number for Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) is RP1097-Dylight594.

Is Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) in stock?

Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate)?

The safety data sheet for Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) is available here: https://www.bosterbio.com/msds?sku=RP1097.

What is Anti-PU.1/Spi1 Antibody (Dylight594 Conjugate) used for?

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.