Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) — image 1 of 3

Product details

Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate)

Catalog number RP1034-PE

Price for RP1034-PE

Size / count 100 µg/Vial

About this product

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody catalog # RP1034. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: RP1034-PE
Size / count: 100 µg/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Background: P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.
Synonyms: Multidrug resistance protein 1;3.6.3.44;ATP-binding cassette sub-family B member 1;P-glycoprotein 1;CD243;ABCB1;MDR1, PGY1;
Gene Name: Multidrug resistance protein 1
UniProt: P08183
Host: Rabbit
Reactivity: Human,Mouse,Rat
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human P Glycoprotein, different from the related rat sequence by twelve amino acids.
Clonality: Polyclonal
Tissue Specificity: Expressed in liver, kidney, small intestine and brain.
Applications: IHC
Purification: Immunogen affinity purified.
Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Applications Notes: Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Mouse, Rat, -<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat<br>
Subcellular Location: Cell membrane ; Multi-pass membrane protein .
Sequence Similarities: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Protein Name: Multidrug resistance protein 1

Frequently Asked Questions

What is the catalog number for Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate)?

The catalog number for Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) is RP1034-PE.

What sizes are available for Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate)?

Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) is available in the following size(s): 100 µg/Vial.

Is Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) in stock?

Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate)?

The safety data sheet for Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) is available here: https://www.bosterbio.com/msds?sku=RP1034.

What is Anti-P Glycoprotein/ABCB1 Antibody (PE Conjugate) used for?

Boster Bio Anti-P Glycoprotein/ABCB1 Antibody catalog # RP1034. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.