Anti-SFTPA1 Antibody Picoband®, PE Conjugate

About this product

Boster Bio Anti-SFTPA1 Antibody catalog # PA1347. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA1347-PE

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Synonyms

Pulmonary surfactant-associated protein A1;PSP-A;PSPA;SP-A;SP-A1;35 kDa pulmonary surfactant-associated protein;Alveolar proteinosis protein;Collectin-4;SFTPA1;COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B;

Gene Name

Pulmonary surfactant-associated protein A1

UniProt

Q8IWL2

Host

Rabbit

Reactivity

Human,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1, different from the rat sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.

Applications

WB

Purification

Immunogen affinity purified.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

Components

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

References & Citations

1. Moore, K. J., D'Amore-Bruno, M. A., Korfhagen, T. R., Glasser, S. W., Whitsett, J. A., Jenkins, N. A., Copeland, N. G. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992. 2. Ramet, M., Lofgren, J., Albo, O.-P., Hallman, M. Surfactant protein-A gene locus associated with recurrent otitis media. J. Pediat. 138: 266-268, 2001.

Storage Conditions

At -20℃ for one year and at 4℃ for one month from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

26242 MW

Observed Molecular Weight

26-35 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Rat<br>

Subcellular Location

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Sequence Similarities

Belongs to the SFTPA family.

Protein Name

Pulmonary surfactant-associated protein A1(PSP-A/PSPA/SP-A/SP-A1)