Anti-MCM9 Antibody Picoband®, HRP Conjugate

About this product

Boster Bio Anti-MCM9 Antibody Picoband® catalog # A07226-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A07226-1-HRP

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1.

Synonyms

MCM9; C6orf61; MCMDC1; DNA helicase MCM9; hMCM9; EC 3.6.4.12; Mini-chromosome maintenance deficient domain-containing protein 1; Minichromosome maintenance 9

Gene Name

minichromosome maintenance 9 homologous recombination repair factor

Gene ID

254394

UniProt

Q9NXL9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MCM9 recombinant protein (Position: M1-L644). Human MCM9 shares 92.7% and 93% amino acid (aa) sequence identity with mouse and rat MCM9, respectively.

Clonality

Polyclonal

Applications

WB, FlowCytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Fauchereau, F., Shalev, S., Chervinsky, E., Beck-Fruchter, R., Legois, B., Fellous, M., Caburet, S., Veitia, R. A. A non-sense MCM9 mutation in a familial case of primary ovarian insufficiency. Clin. Genet. 89: 603-607, 2016. 2. Lutzmann, M., Grey, C., Traver, S., Ganier, O., Maya-Mendoza, A., Ranisavljevic, N., Bernex, F., Nishiyama, A., Montel, N., Gavois, E., Forichon, L., de Massy, B., Mechali, M. MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination. Molec. Cell 47: 523-534, 2012. 3. Lutzmann, M., Maiorano, D., Mechali, M. Identification of full genes and proteins of MCM9, a novel, vertebrate-specific member of the MCM2-8 protein family. Gene 362: 51-56, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

127 kDa

Observed Molecular Weight

127 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human<br> ELISA, 0.1-0.5 μg/ml, Human<br>

Protein Name

DNA helicase MCM9