Anti-NAXE Antibody Picoband®, APC Conjugate

About this product

Boster Bio Anti-NAXE Antibody Picoband® catalog # A10537-1. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A10537-1-APC

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene. The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes.

Gene Name

NAXE

Gene ID

128240

UniProt

Q8NCW5

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

E.coli-derived human NAXE recombinant protein (Position: R46-Q288). Human NAXE shares 93% and 94.2% amino acid (aa) sequence identity with mouse and rat NAXE, respectively.

Clonality

Polyclonal

Applications

WB,IHC,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Fang, L., Choi, S.-H., Baek, J. S., Liu, C., Almazan, F., Ulrich, F., Wiesner, P., Taleb, A., Deer, E., Pattison, J., Torres-Vazquez, J., Li, A. C., Miller, Y. I. Control of angiogenesis by AIBP-mediated cholesterol efflux. Nature 498: 118-122, 2013. 2. Kremer, L. S., Danhauser, K., Herebian, D., Ramadza, D. P., Piekutowska-Abramczuk, D., Seibt, A., Muller-Felber, W., Haack T. B., Ploski, R., Lohmeier, K., Schneider, D., Klee, D., and 10 others. NAXE mutations disrupt the cellular NAD(P)HX repair system and cause a lethal neurometabolic disorder of early childhood. Am. J. Hum. Genet. 99: 894-902, 2016. 3. Marbaix, A. Y., Tyteca, D., Niehaus, T. D., Hanson, A. D., Linster, C. L., Van Schaftingen, E. Occurrence and subcellular distribution of the NAD(P)HX repair system in mammals. Biochem. J. 460: 49-58, 2014.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5 μg/ml, Human, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>