Anti-Fibroblast growth factor 9 FGF9 Antibody Picoband®, APC Conjugate

About this product

Boster Bio Anti-Fibroblast growth factor 9 FGF9 Antibody catalog # PA1453. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA1453-APC

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

FGF 9, Fibroblast growth factor 9, is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF 9 gene contains 3 exons. By radioactive chromosomal in situ hybridization, the FGF 9 gene is mapped to chromosome 13q11-q12. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling.

Synonyms

Fibroblast growth factor 9;FGF-9;Glia-activating factor;GAF;Heparin-binding growth factor 9;HBGF-9;FGF9;

Gene Name

Fibroblast growth factor 9

UniProt

P31371

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human FGF9, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Glial cells.

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. .

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

References & Citations

1. Mariani, F. V., Ahn, C. P., Martin, G. R.Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning.Nature 453: 401-405, 2008. 2. Mattei, M.-G., Penault-Llorca, F., Coulier, F., Birnbaum, D.The human FGF 9 gene maps to chromosomal region 13q11-q12.Genomics 29: 811-812, 1995. 3. Sun, X., Lewandoski, M., Meyers, E. N., Liu, Y.-H., Maxson, R. E., Jr., Martin, G. R.Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development.Nature Genet. 25: 83-86, 2000.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

23441 MW

Observed Molecular Weight

23 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, Mouse, By Heat<br>Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse<br>

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the heparin-binding growth factors family.

Protein Name

Fibroblast growth factor 9(FGF-9)