Anti-Nucleoplasmin-2 NPM2 Antibody Picoband®, APC Conjugate

About this product

Boster Bio Anti-Nucleoplasmin-2 NPM2 Antibody catalog # PA1991. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA1991-APC

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

NPM2 (Nucleophosmin/Nucleoplasmin Family Member 2), Burns et al. (2003) mapped the mouse Npm2 gene to chromosome 14. Burns et al. (2003) found that female Npm2-null mice showed defects in preimplantation embryo development, with abnormalities in oocyte and early embryonic nuclei.

Synonyms

Nucleoplasmin-2;NPM2;

Gene Name

Nucleoplasmin-2

UniProt

Q86SE8

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human NPM2.

Clonality

Polyclonal

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. .

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

References & Citations

1. Burns, K. H., Viveiros, M. M., Ren, Y., Wang, P., DeMayo, F. J., Frail, D. E., Eppig, J. J., Matzuk, M. M. Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science 300: 633-636, 2003.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

24152 MW

Observed Molecular Weight

85-91 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Nucleus . Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm. .

Protein Name

Nucleoplasmin-2