Anti-Gastrotropin FABP6 Antibody Picoband®, APC Conjugate

About this product

Boster Bio Anti-Gastrotropin FABP6 Antibody catalog # PA2158. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA2158-APC

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fatty acid binding protein 6, ileal, also called FABP6 or ILBP is a protein which in humans is encoded by the FABP6 gene. Ileal lipid-binding protein (ILBP) is a member of a family of intracellular fatty acid, retinoid, and bile acid-binding proteins. This gene is mapped to 5q33.3. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is though that FABPs roles include fatty acid uptake, transport, and metabolism.

Synonyms

Gastrotropin;GT;Fatty acid-binding protein 6;Ileal lipid-binding protein;ILBP;Intestinal 15 kDa protein;I-15P;Intestinal bile acid-binding protein;I-BABP;FABP6;ILBP, ILLBP;

Gene Name

Gastrotropin

UniProt

P51161

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human FABP6.

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. .

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. .

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

References & Citations

1. Birkenmeier, E. H., Rowe, L. B., Crossman, M. W., Gordon, J. I. Ileal lipid-binding protein (Illbp) gene maps to mouse chromosome 11. Mammalian Genome 5: 805-806, 1994. 2. Oelkers, P., Dawson, P. A. Cloning and chromosomal localization of the human ileal lipid-binding protein. Biochim. Biophys. Acta 1257: 199-202, 1995.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14371 MW

Observed Molecular Weight

14 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat<br>Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Isoform 1: Cytoplasm.

Sequence Similarities

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein Name

Gastrotropin