Anti-CAT1/SLC7A1 Antibody Picoband®, APC Conjugate

About this product

Boster Bio Anti-CAT1/SLC7A1 Antibody catalog # PA2245. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA2245-APC

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

High affinity cationic amino acid transporter 1, also called solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1) or ATRC1 is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. This gene is high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.

Synonyms

High affinity cationic amino acid transporter 1;CAT-1;CAT1;Ecotropic retroviral leukemia receptor homolog;Ecotropic retrovirus receptor homolog;ERR;Solute carrier family 7 member 1;System Y+ basic amino acid transporter;SLC7A1;ATRC1, ERR, REC1L;

Gene Name

High affinity cationic amino acid transporter 1

UniProt

P30825

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CAT1, different from the related mouse and rat sequences by four amino acids.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. .

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. .

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

References & Citations

1. Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I., Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125: 1111-1124, 2006. 2. Bowcock, A. M., Gerken, S. C., Barnes, R. I., Shiang, R., Jabs, E. W., Warren, A. C., Antonarakis, S., Retief, A. E., Vergnaud, G., Leppert, M., Lalouel, J.-M., White, R. L., Cavalli-Sforza, L. L. The CEPH consortium linkage map of human chromosome 13. Genomics 16: 486-496, 1993. 3. Kozak, C. A., Albritton, L. M., Cunningham, J. M. Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses. J. Virol. 64: 3119-3121, 1990.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

67638 MW

Observed Molecular Weight

73 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Sequence Similarities

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Protein Name

High affinity cationic amino acid transporter 1