Anti-LSM11 Antibody Picoband®, iFluor647 Conjugate

About this product

Boster Bio Anti-LSM11 Antibody Picoband® catalog # A11132-1. Tested in WB, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A11132-1-iFluor647

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

LSM11 is a component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing .Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cellcycle progression from G1 to S phases.

Gene Name

LSM11

Gene ID

134353

UniProt

P83369

Host

Rabbit

Reactivity

Human,Rat

Immunogen

E.coli-derived human LSM11 recombinant protein (Position: A17-Q360). Human LSM11 shares 88.4% amino acid (aa) sequence identity with mouse LSM11.

Clonality

Polyclonal

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/15/2018. 2. Pillai, R. S., Grimmler, M., Meister, G., Will, C. L., Luhrmann, R., Fischer, U., Schumperli, D. Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev. 17: 2321-2333, 2003. 3. Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M.-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., Albawardi, W., Fremond, M.-L., and 44 others. cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing. Nature Genet. 52: 1364-1372, 2020.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

68 kDa

Applications Notes

Western blot, 0.25-0.5 μg/ml, Rat<br> ELISA, 0.1-0.5 μg/ml, -<br>