Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) — image 1 of 2

Product details

Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate)

Catalog number RP1097-carrier-free

Price for RP1097-carrier-free

Size / count 100 µg/Vial

About this product

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: RP1097-carrier-free
Size / count: 100 µg/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Transcription factor PU.1;31 kDa-transforming protein;SPI1;
Gene Name: Transcription factor PU.1
UniProt: P17947
Host: Rabbit
Reactivity: Human,Mouse,Rat
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: E.coli-derived human PU.1/Spi1 recombinant protein (Position: E18-K196). Human PU.1/Spi1 shares 84% and 84.4% amino acid (aa) sequence identity with mouse and rat PU.1/Spi1, respectively.
Clonality: Polyclonal
Applications: IHC
Purification: Immunogen affinity purified.
Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function: Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity). .
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Applications Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat <br>
Subcellular Location: Nucleus .
Protein Name: Transcription factor PU.1

Frequently Asked Questions

What is the catalog number for Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate)?

The catalog number for Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) is RP1097-carrier-free.

What sizes are available for Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate)?

Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) is available in the following size(s): 100 µg/Vial.

Is Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) in stock?

Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate)?

The safety data sheet for Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) is available here: https://www.bosterbio.com/msds?sku=RP1097.

What is Anti-PU.1/Spi1 Antibody (Carrier-free Conjugate) used for?

Boster Bio Anti-PU.1/Spi1 Antibody catalog # RP1097. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.