Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free

Catalog number A01600-Dyl488-carrier-free

Discontinued

Price for A01600-Dyl488-carrier-free

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-Human ATF1 DyLight® 488 conjugated Antibody catalog # A01600-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number: A01600-Dyl488-carrier-free
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
Synonyms: Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36; ATF1
Gene Name: activating transcription factor 1
Gene ID: 466
UniProt: P18846
Host: Rabbit
Reactivity: Human
Cross Reactivity: No cross-reactivity with other proteins.
Immunogen: E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.
Clonality: Polyclonal
Label: DyLight®488
Applications: Flow Cytometry
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Components: Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
References & Citations: 1. ucman, J., Delattre, O., Desmaze, C., Epstein, A. L., Stenman, G., Speleman, F., Fletchers, C. D. M., Aurias, A., Thomas, G. EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nature Genet. 4: 341-345, 1993. 2. "Entrez Gene: ATF1 activating transcription factor 1"
Storage Conditions: At -20℃ for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Observed Molecular Weight: 39 kDa
Fragment: Rabbit IgG
Specificity: No cross reactivity with other proteins.
Applications Notes: Flow Cytometry (Fixed), 1-3μg/1x10<sup>6</sup> cells
Subcellular Location: Nucleus.

Frequently Asked Questions

What is the catalog number for Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free?

The catalog number for Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free is A01600-Dyl488-carrier-free.

Is Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free in stock?

Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free?

The safety data sheet for Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free is available here: https://www.bosterbio.com/msds?sku=A01600-Dyl488.

What is Anti-Human ATF1 DyLight® 488 conjugated Antibody, Carrier-free used for?

Boster Bio Anti-Human ATF1 DyLight® 488 conjugated Antibody catalog # A01600-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.