Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1), Carrier-free

About this product

Boster Bio Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1) catalog # MA1032. Tested in ICC, WB applications. This antibody reacts with Bovine, Human, Mouse.

Specifications

Catalog number

MA1032-carrier-free

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

The mammalian A-type cyclin family consists of 2 members, cyclin A1 (CCNA1) and cyclin A2 (CCNA2). Human cyclin A gene is assigned to 4q26-q27. Cyclin A protein is synthesized and localized into the nucleus at the onset of S phase in nontransformed mammalian fibroblasts.

Synonyms

Cyclin-A2;Cyclin-A;Ccna2;Ccna, Cyca;

Gene Name

Cyclin-A2

Gene ID

Human(890), Mouse(12428), Rat(114494)

UniProt

P51943

Host

Mouse

Reactivity

Bovine,Human,Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Recombinant bovine cyclin A.

Clonality

Monoclonal

Clone

Clone: CY-A1

Tissue Specificity

Ubiquitous. In the testis, expressed in germ cells and in the ovary, in both germline and somatic cells.

Applications

ICC,WB

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. .

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

References & Citations

1. Blanquet, V.; Wang, J.; Chenivesse, X.; Henglein, B.; Garreau, F.; Brechot, C.; Turleau, C. : Assignment of a human cyclin A gene to 4q26-q27. Genomics 8: 595-597, 1990. 2. Girard, F.; Strausfeld, U.; Fernandez, A.; Lamb, N. J. C. : Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67: 1169-1179, 1991.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

47269 MW

Observed Molecular Weight

55 kDa

Fragment

Mouse IgG2a

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunocytochemistry , 1μg/ml, Human, bovine , mouse, -<br>Western blot, 0.5-1μg/ml, Human, bovine , mouse<br>

Subcellular Location

Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER. .

Sequence Similarities

Belongs to the cyclin family. Cyclin AB subfamily.

Protein Name

Cyclin-A2