Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free

Catalog number MA1060-carrier-free

Discontinued

Price for MA1060-carrier-free

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-P-GlycoProtein (MDR) ABCB1 Antibody (Monoclonal, F4) catalog # MA1060. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Specifications

Catalog number: MA1060-carrier-free
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: P-Glycoprotein,, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Synonyms: Multidrug resistance protein 1A;3.6.3.44;ATP-binding cassette sub-family B member 1A;MDR1A;Multidrug resistance protein 3;P-glycoprotein 3;Abcb1a;Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3;
Gene Name: DNA helicase
Gene ID: Human(5243), Mouse(18671), Rat(170913)
UniProt: P08183
Host: Mouse
Reactivity: Human
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: Mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Clonality: Monoclonal
Clone: Clone: F4
Tissue Specificity: ABCB1: Expressed in liver, kidney, small intestineand brain.
Applications: IHC,ICC,WB
Purification: Ascites
Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Form: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Function: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .
Components: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
References & Citations: 1. Callen, D. F.; Baker, E.; Simmers, R. N.; Seshadri, R.; Roninson, I. B. : Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. Hum. Genet. 77: 142-144, 1987. 2. de Lannoy, I. A. M.; Silverman, M. : The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem. Biophys. Res. Commun. 189: 551-557, 1992.
Storage Conditions: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 140647 MW
Observed Molecular Weight: 200 kDa
Fragment: Mouse IgG1
Specificity: No cross reactivity with other proteins.
Applications Notes: Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, By Heat <br>Immunocytochemistry , 1μg/ml, Human, -<br>Immunohistochemistry (Frozen Section), 1-2μg/ml, Human, -<br>Western blot, 0.5-1μg/ml, Human<br>
Subcellular Location: Cell membrane; Multi-pass membrane protein.
Sequence Similarities: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Protein Name: DNA replication licensing factor MCM7

Frequently Asked Questions

What is the catalog number for Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free?

The catalog number for Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free is MA1060-carrier-free.

Is Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free in stock?

Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free?

The safety data sheet for Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free is available here: https://www.bosterbio.com/msds?sku=MA1060.

What is Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4), Carrier-free used for?

Boster Bio Anti-P-GlycoProtein (MDR) ABCB1 Antibody (Monoclonal, F4) catalog # MA1060. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.