Anti-mGluR2 GRM2 Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-mGluR2 GRM2 Rabbit Monoclonal Antibody catalog # M06123. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M06123-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Metabotropic glutamate receptor 2;mGluR2;GRM2;GPRC1B, MGLUR2;

Gene Name

Metabotropic glutamate receptor 2

UniProt

Q14416

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human mGluR2

Clonality

Monoclonal

Clone

Clone: IEI-7

Tissue Specificity

Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. .

Applications

WB,IHC,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

95568 MW

Observed Molecular Weight

25 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:5000-1:10000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse . Cell projection, dendrite .

Protein Name

T-cell surface glycoprotein CD3 zeta chain