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Product details

Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free

Catalog number M00334-2-carrier-free

Discontinued

Price for M00334-2-carrier-free

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody catalog # M00334-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
M00334-2-carrier-free
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Synonyms
Caspase-3;CASP-3;3.4.22.56;Apopain;Cysteine protease CPP32;CPP-32;Protein Yama;SREBP cleavage activity 1;SCA-1;Caspase-3 subunit p17;Caspase-3 subunit p12;CASP3;CPP32;
Gene Name
Caspase-3
UniProt
P42574
Host
Rabbit
Reactivity
Human,Mouse,Rat
Immunogen
A synthesized peptide derived from human Caspase-3 p12
Clonality
Monoclonal
Clone
Clone: GEA-3
Tissue Specificity
Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Applications
WB,IHC,ICC,IF,IP
Purification
Affinity-chromatography
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. .
Components
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Storage Conditions
Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
31608 MW
Observed Molecular Weight
47 kDa
Fragment
Rabbit IgG
Applications Notes
WB 1:500-1:1000<br>IHC 1:100-1:500<br>ICC/IF 1:50-1:200<br>IP 1:50
Subcellular Location
Cytoplasm.
Protein Name
P2X purinoceptor 1

Frequently Asked Questions

What is the catalog number for Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free?

The catalog number for Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free is M00334-2-carrier-free.

Is Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free in stock?

Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free?

The safety data sheet for Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free is available here: https://www.bosterbio.com/msds?sku=M00334-2.

What is Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody, Carrier-free used for?

Boster Bio Anti-Caspase-3 p12 CASP3 Rabbit Monoclonal Antibody catalog # M00334-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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