Anti-Cytokeratin 4 KRT4 Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-Cytokeratin 4 KRT4 Rabbit Monoclonal Antibody catalog # M07410. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Rat.

Specifications

Catalog number

M07410-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Keratin, type II cytoskeletal 4;Cytokeratin-4;CK-4;Keratin-4;K4;Type-II keratin Kb4;KRT4;CYK4;

Gene Name

Keratin, type II cytoskeletal 4

UniProt

P19013

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human Cytokeratin 4

Clonality

Monoclonal

Clone

Clone: GFO-11

Tissue Specificity

Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer. .

Applications

WB,IHC,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

57285 MW

Observed Molecular Weight

47 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200

Subcellular Location

Nucleus. Chromosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain