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Product details

Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free

Catalog number M00953-1-carrier-free

Discontinued

Price for M00953-1-carrier-free

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody catalog # M00953-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
M00953-1-carrier-free
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
Synonyms
DNA topoisomerase 2-alpha;5.99.1.3;DNA topoisomerase II, alpha isozyme;TOP2A;TOP2;
Gene Name
DNA topoisomerase 2-alpha
UniProt
P11388
Host
Rabbit
Reactivity
Human,Mouse,Rat
Immunogen
A synthesized peptide derived from human Topoisomerase II alpha
Clonality
Monoclonal
Clone
Clone: FB-20
Tissue Specificity
Expressed in the excretory system, thyroid gland and Wilms tumors.
Applications
WB,IHC,IP
Purification
Affinity-chromatography
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Function
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity). .
Components
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Storage Conditions
Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
174385 MW
Observed Molecular Weight
28 kDa
Fragment
Rabbit IgG
Applications Notes
WB 1:500-1:2000<br>IHC 1:50-1:200<br>IP 1:50
Subcellular Location
Cytoplasm . Nucleus, nucleoplasm . Generally located in the nucleoplasm.
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)

Frequently Asked Questions

What is the catalog number for Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free?

The catalog number for Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free is M00953-1-carrier-free.

Is Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free in stock?

Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free?

The safety data sheet for Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free is available here: https://www.bosterbio.com/msds?sku=M00953-1.

What is Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody, Carrier-free used for?

Boster Bio Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody catalog # M00953-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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