Anti-Histone H2A (hydroxyl Y39) HIST1H2AB Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-Histone H2A (hydroxyl Y39) HIST1H2AB Rabbit Monoclonal Antibody catalog # M16777-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M16777-1-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Phospho Site

Y39

Synonyms

Histone H2A type 1-B/E;Histone H2A.2;Histone H2A/a;Histone H2A/m;HIST1H2AB;H2AFM;HIST1H2AE;H2AFA;

Gene Name

Histone H2A type 1-B/E

UniProt

P04908

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Histone H2A (hydroxyl Y39)

Clonality

Monoclonal

Clone

Clone: DED-8

Tissue Specificity

Widely expressed with highest levels in brain, kidney and muscle. .

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14135 MW

Observed Molecular Weight

37 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:500-1:2000

Subcellular Location

Nucleus. Chromosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain