Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free — image 1 of 2

Product details

Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free

Catalog number M00029-carrier-free

Discontinued

Price for M00029-carrier-free

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-PI 3 kinase p110 alpha Monoclonal Antibody catalog # M00029. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M00029-carrier-free
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Synonyms: Signal transducer and activator of transcription 3;Acute-phase response factor;STAT3;APRF;
Gene Name: Signal transducer and activator of transcription 3
UniProt: P42336
Host: Rabbit
Reactivity: Human,Mouse,Rat
Immunogen: A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha
Clonality: Monoclonal
Clone: Clone: BEB-16
Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Applications: WB,ICC,IF,IP
Purification: Affinity-chromatography
Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). .
Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 88068 MW
Observed Molecular Weight: 131 kDa
Fragment: Rabbit IgG
Applications Notes: WB 1:1000-1:2000<br>ICC/IF 1:50-1:200<br>IP 1:20
Subcellular Location: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.
Protein Name: P2X purinoceptor 1

Frequently Asked Questions

What is the catalog number for Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free?

The catalog number for Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free is M00029-carrier-free.

Is Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free in stock?

Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free?

The safety data sheet for Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free is available here: https://www.bosterbio.com/msds?sku=M00029.

What is Anti-PI 3 kinase p110 alpha Monoclonal Antibody, Carrier-free used for?

Boster Bio Anti-PI 3 kinase p110 alpha Monoclonal Antibody catalog # M00029. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.