Anti-Factor IX Rabbit Monoclonal Antibody , Carrier-free

About this product

Boster Bio Anti-Factor IX Rabbit Monoclonal Antibody catalog # M00537. Tested in WB application. This antibody reacts with Human.

Specifications

Catalog number

M00537-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Mixed lineage kinase domain-like protein;hMLKL;MLKL ;

Gene Name

Mixed lineage kinase domain-like protein

UniProt

P00740

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Factor IX

Clonality

Monoclonal

Clone

Clone: 18F05

Tissue Specificity

Detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform 2 is strongly expressed in placenta. Isoform 3 is expressed in corneal epithelial cells (at protein level). Isoform 3 is expressed in vascular smooth muscle cells (VSMC). .

Applications

WB

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54479 MW

Observed Molecular Weight

54 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Cytoplasm . Cell membrane . Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.

Protein Name

T-cell surface glycoprotein CD4