Anti-Human IgG1 Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-Human IgG1 Rabbit Monoclonal Antibody catalog # M04575-6. Tested in WB application. This antibody reacts with Human.

Specifications

Catalog number

M04575-6-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Ig gamma-1 chain C region;IGHG1;

Gene Name

Ig gamma-1 chain C region

UniProt

P01857

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IgG1

Clonality

Monoclonal

Clone

Clone: 27I03

Tissue Specificity

According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.

Applications

WB

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36106 MW

Observed Molecular Weight

52 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Secreted.

Protein Name

T-cell surface glycoprotein CD3 zeta chain