Anti-Cyclin H/p34 Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-Cyclin H/p34 Rabbit Monoclonal Antibody catalog # M03013-3. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M03013-3-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Cyclin-H;MO15-associated protein;p34;p37;CCNH;

Gene Name

Cyclin-H

UniProt

P51946

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Cyclin H/p34

Clonality

Monoclonal

Clone

Clone: 28C49

Tissue Specificity

Activated T-lymphocytes.

Applications

WB

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37643 MW

Observed Molecular Weight

35 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Nucleus.

Protein Name

T-cell surface glycoprotein CD3 zeta chain