Anti-IFT88 Rabbit Monoclonal Antibody, Carrier-free

About this product

Boster Bio Anti-IFT88 Rabbit Monoclonal Antibody catalog # M06814. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M06814-carrier-free

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Keratin, type I cytoskeletal 15;Cytokeratin-15;CK-15;Keratin-15;K15;KRT15;KRTB;

Gene Name

Keratin, type I cytoskeletal 15

UniProt

Q13099

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human IFT88

Clonality

Monoclonal

Clone

Clone: 29I92

Tissue Specificity

Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. .

Applications

WB

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

49212 MW

Observed Molecular Weight

94 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Cytoplasm .

Protein Name

T-cell surface glycoprotein CD3 zeta chain