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Product details

Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free

Catalog number EZ1691-carrier-free

Discontinued

Price for EZ1691-carrier-free

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Size / count 5 Plates/Kit

This variant is discontinued and cannot be added to your cart.

About this product

Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human B2M in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.

Specifications

Catalog number
EZ1691-carrier-free
Size / count
5 Plates/Kit
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Synonyms
Beta-2-microglobulin; Beta-2-microglobulin form pI 5.3; B2M; CDABP0092; HDCMA22P
Gene Name
beta-2-microglobulin
Gene ID
567
UniProt
P61769
Reactivity
Human
Cross Reactivity
There is no detectable cross-reactivity with other relevant proteins.
Immunogen
Expression system for standard: from plasma
Applications
ELISA
Sample Type
cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Detection Range
156 pg/ml - 10,000 pg/ml
Function
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Components
Description Capture Antibody Detection Antibody Avidin-Biotin-Peroxidase Complex (ABC) Lyophilized Standard|
Storage Conditions
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Specificity
Natural and recombinant human B2M
Anticoagulant
heparin or EDTA
Subcellular Location
Secreted.

Frequently Asked Questions

What is the catalog number for Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free?

The catalog number for Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free is EZ1691-carrier-free.

Is Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free in stock?

Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free?

The safety data sheet for Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free is available here: https://www.bosterbio.com/msds?sku=EZ1691.

What is Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free used for?

Human B2M ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human B2M in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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