Recombinant Human CNTF Protein, Carrier-free

Catalog number R00609-carrier-free

Discontinued

Price for R00609-carrier-free

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Ciliary Neurotrophic Factor (CNTF) is a cytokine belonging to the Interleukin 6 (IL-6) family, which also includes IL-6, Oncostatin M, Leukemia Inhibitory Factor (LIF), and Cardiotrophin-1. Structurally, CNTF resembles a four-helix bundle composition, similar to the other members of the IL-6 family. The receptor for CNTF is composed of three parts: a gp130-like subunit common in the IL-6 receptor family, a LIF Receptor β subunit, and a CNTF specific α receptor subunit. Upon binding to the CNTF, the β subunit of the CNTF receptorwill undergo tyrosine phosphorylation, and activate the intracellular JAK/STAT pathway. The main function of CNTF in vivo is to promote the differentiation and survival of a variety of neurons and glial cells, including sympathetic precursor cells and spinal motor neurons. Recombinant human Ciliary Neurotrophic Factor (rhCNTF) produced in E. coli is a single non-glycosylated polypeptide chain containing 199 amino acids. A fully biologically active molecule, rhCNTF has a molecular mass of 22.8 kDa analyzed by reducing SDS-PAGE.

Specifications

Catalog number: R00609-carrier-free
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Gene Name: CNTF
UniProt: P26441
Reactivity: Human
Source: E. coli His12-Met200
Sequence: HRRDL CSRSI WLARK IRSDL TALTE SYVKH QGLNK NINLD SADGM PVAST DQWSE LTEAE RLQEN LQAYR TFHVL LARLL EDQQV HFTPT EGDFH QAIHT LLLQV AAFAY QIEEL MILLE YKIPR NEADG MPINV GDGGL FEKKL WGLKV LQELS QWTVR SIHDL RFISS HQTGI PARGS HYIAN NKKM
Purification: >95%, by SDS-PAGE quantitative densitometry by Coomassie? Blue Staining.
Endotoxin: Less than 1 EU/μg of rhCNTF as determined by LAL method.
Form: Lyophilized
Components: Lyophilized after extensive dialysis against PBS.
Storage Conditions: Lyophilized recombinant human Ciliary Neurotrophic Factor (rhCNTF)remains stable up to 6 months at -80℃ from date of receipt. Upon reconstitution, rhCNTF remains stable up to 2 weeks at 4℃ or up to 3 months at -20℃.
Calculated Molecular Weight: 21.7KD

Frequently Asked Questions

What is the catalog number for Recombinant Human CNTF Protein, Carrier-free?

The catalog number for Recombinant Human CNTF Protein, Carrier-free is R00609-carrier-free.

Is Recombinant Human CNTF Protein, Carrier-free in stock?

Recombinant Human CNTF Protein, Carrier-free is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human CNTF Protein, Carrier-free?

The safety data sheet for Recombinant Human CNTF Protein, Carrier-free is available here: https://www.bosterbio.com/msds?sku=R00609.

What is Recombinant Human CNTF Protein, Carrier-free used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.