Anti-RAD51 Antibody

Catalog number M00088-2-01

Discontinued

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About this product

Boster Bio Anti-RAD51 Antibody (Catalog # M00088-2) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M00088-2-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Synonyms: DNA repair protein RAD51 homolog 1, HsRAD51, hRAD51, RAD51 homolog A, RAD51, RAD51A, RECA
Gene Name: RAD51
UniProt: Q06609
Host: Mouse
Reactivity: Human
Immunogen: This RAD51 antibody is generated from a mouse immunized with a recombinant protein between 1-339 amino acids from human RAD51.
Clonality: Monoclonal
Clone: Clone: 1690CT361.33.68
Tissue Specificity: Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast
Applications: WB
Field of Research: Mitochondria
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution: WB: 1:4000
Function: 184175352034810112205100202313642375437623509288285756582668130818417535203481011220510020231364237543762350928828575658266813081841753520348101122051002023136423754376235092882857565826681308277978183184404524141787124421712041359326253028
Molecular Weight: 36966 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG2b, k
Subcellular Location: Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage (PubMed:20154705) . DNA damage induces an increase in nuclear levels (PubMed:20154705) . Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment (PubMed:23754376) . Accumulated at sites of DNA damage in a SPIDR- dependent manner (PubMed:23509288) . Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner (PubMed:23401855) . Colocalizes with ERCC5/XPG to nuclear foci in S phase (PubMed:26833090) . Recruited to stalled replication forks during replication stress by the TONSL-MMS22L complex, as well as ATAD5 and WDR48 in an ATR-dependent manner (PubMed:27797818, PubMed:31844045) .

Frequently Asked Questions

What is the catalog number for Anti-RAD51 Antibody?

The catalog number for Anti-RAD51 Antibody is M00088-2.

Is Anti-RAD51 Antibody in stock?

Anti-RAD51 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-RAD51 Antibody?

The safety data sheet for Anti-RAD51 Antibody is available here: https://www.bosterbio.com/msds?sku=M00088-2.

What is Anti-RAD51 Antibody used for?

Boster Bio Anti-RAD51 Antibody (Catalog # M00088-2) . Tested in WB application (s) . This antibody reacts with Human.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.