Anti-GLS Antibody (C-Term)

Catalog number M01272-1-01

Discontinued

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About this product

Boster Bio Anti-GLS Antibody (C-Term) (Catalog # M01272-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: M01272-1-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
Synonyms: Glutaminase kidney isoform, mitochondrial, GLS, K-glutaminase, L-glutamine amidohydrolase, GLS, GLS1, KIAA0838
Gene Name: GLS
UniProt: O94925
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: This GLS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 555-587 amino acids from human GLS.
Clonality: Polyclonal
Tissue Specificity: Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle.
Applications: WB
Field of Research: Metabolism, Neuroscience, Signal Transduction, Mitochondria
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution: WB: 1:2000
Function: 305758543023972130970188
Molecular Weight: 73461 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: Rabbit IgG
Subcellular Location: [Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:P13264}. Cytoplasm, cytosol. Note=The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits {ECO:0000250|UniProtKB:P13264} [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix {ECO:0000250|UniProtKB:P13264} Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. {ECO:0000250|UniProtKB:P13264}

Frequently Asked Questions

What is the catalog number for Anti-GLS Antibody (C-Term)?

The catalog number for Anti-GLS Antibody (C-Term) is M01272-1.

Is Anti-GLS Antibody (C-Term) in stock?

Anti-GLS Antibody (C-Term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GLS Antibody (C-Term)?

The safety data sheet for Anti-GLS Antibody (C-Term) is available here: https://www.bosterbio.com/msds?sku=M01272-1.

What is Anti-GLS Antibody (C-Term) used for?

Boster Bio Anti-GLS Antibody (C-Term) (Catalog # M01272-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.