Anti-Profilin-1 Antibody

About this product

Boster Bio Anti-Profilin-1 Antibody (Catalog # M01480-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01480-1-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Synonyms

Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1

Gene Name

PFN1

UniProt

P07737

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This Profilin-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-140 amino acids from the human region of human Profilin-1.

Clonality

Polyclonal

Tissue Specificity

Expressed in epididymis (at protein level) .

Applications

WB, Flow Cytometry

Field of Research

Cancer, Cell Biology, Neuroscience, Signal Transduction, Viral process

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Molecular Weight

15054 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

Cytoplasm, cytoskeleton.

Prediction Reactivity

Bovine