Product details

Anti-MBD2 Antibody

Catalog number M01746-1-01

Discontinued

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About this product

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: M01746-1-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Synonyms: Methyl-CpG-binding domain protein 2, Demethylase, DMTase, Methyl-CpG-binding protein MBD2, MBD2
Gene Name: MBD2
UniProt: Q9UBB5
Host: Mouse
Reactivity: Human
Immunogen: This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
Clonality: Monoclonal
Clone: Clone: 1812CT625.9.45
Tissue Specificity: Highly expressed in brain, heart, kidney, stomach, testis and placenta.
Applications: WB, IHC-P
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 97746691094785224307175104714991094785216428440289776661047149910947852164151791641517912665568
Molecular Weight: 43255 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, k
Subcellular Location: Nucleus. Chromosome Note=Nuclear, in discrete foci (PubMed:12183469) . Detected at replication foci in late S phase. Localizes to methylated chromatin (PubMed:16428440) . Localizes to sites of DNA damage in a manner partially dependent on ZMYND8 (PubMed:27732854)

Frequently Asked Questions

What is the catalog number for Anti-MBD2 Antibody?

The catalog number for Anti-MBD2 Antibody is M01746-1.

Is Anti-MBD2 Antibody in stock?

Anti-MBD2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MBD2 Antibody?

The safety data sheet for Anti-MBD2 Antibody is available here: https://www.bosterbio.com/msds?sku=M01746-1.

What is Anti-MBD2 Antibody used for?

Boster Bio Anti-MBD2 Antibody (Catalog # M01746-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.