Anti-Phospho-eEF2k (Ser366) Antibody

About this product

Boster Bio Anti-Phospho-eEF2k (Ser366) Antibody (Catalog # M02277) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

M02277-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Synonyms

Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K

Gene Name

EEF2K

UniProt

O00418

Host

Rabbit

Reactivity

Human

Immunogen

This Phospho-eEF2k (Ser366) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-371 amino acids from the human region of human EEF2k.

Clonality

Polyclonal

Applications

WB

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:500

Function

Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Molecular Weight

82144 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG