Anti-XRN1 Antibody

Catalog number M02855-01

Discontinued

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About this product

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M02855-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Synonyms: 5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1
Gene Name: XRN1
UniProt: Q8IZH2
Host: Mouse
Reactivity: Human
Immunogen: This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.
Clonality: Monoclonal
Clone: Clone: 1647CT536.85.48
Tissue Specificity: Expressed in heart, brain, pancreas, spleen, testis, osteogenic sarcoma (OGS) biopsy and primary cell lines
Applications: WB
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution: WB: 1:2000
Function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity) . Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) .
Molecular Weight: 194107 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, k
Subcellular Location: Cytoplasm. Note=Discrete foci at the inner surface of the cell membrane

Frequently Asked Questions

What is the catalog number for Anti-XRN1 Antibody?

The catalog number for Anti-XRN1 Antibody is M02855.

Is Anti-XRN1 Antibody in stock?

Anti-XRN1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-XRN1 Antibody?

The safety data sheet for Anti-XRN1 Antibody is available here: https://www.bosterbio.com/msds?sku=M02855.

What is Anti-XRN1 Antibody used for?

Boster Bio Anti-XRN1 Antibody (Catalog # M02855) . Tested in WB application (s) . This antibody reacts with Human.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.