Anti-RBCK1 (UBCE7IP3) Antibody

Catalog number M04562-01

Discontinued

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About this product

Boster Bio Anti-RBCK1 (UBCE7IP3) Antibody (Catalog # M04562) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: M04562-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF- kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF- RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
Synonyms: RanBP-type and C3HC4-type zinc finger-containing protein 1, 6.3.2.-, HBV-associated factor 4, Heme-oxidized IRP2 ubiquitin ligase 1, HOIL-1, Hepatitis B virus X-associated protein 4, RING finger protein 54, Ubiquitin-conjugating enzyme 7-interacting protein 3, RBCK1, C20orf18, RNF54, UBCE7IP3, XAP3, XAP4
Gene Name: RBCK1
UniProt: Q9BYM8
Host: Mouse
Reactivity: Human
Immunogen: This RBCK1 (UBCE7IP3) antibody is generated from a mouse immunized with a recombinant protein of human RBCK1 (UBCE7IP3) .
Clonality: Monoclonal
Clone: Clone: 1839CT718.19.54
Applications: WB
Field of Research: Cell Biology, Viral process, Host-Virus Interaction
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution: WB: 1:2000
Function: 12629548174494681871144812629548174494681871144817006537214551732145518021455181191369681700653721455173214551802145518119136968170065372145517321455180214551811700653721455173214551802145518119136968284813312848133128481331237089982000584621455181
Molecular Weight: 57572 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, k

Frequently Asked Questions

What is the catalog number for Anti-RBCK1 (UBCE7IP3) Antibody?

The catalog number for Anti-RBCK1 (UBCE7IP3) Antibody is M04562.

Is Anti-RBCK1 (UBCE7IP3) Antibody in stock?

Anti-RBCK1 (UBCE7IP3) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-RBCK1 (UBCE7IP3) Antibody?

The safety data sheet for Anti-RBCK1 (UBCE7IP3) Antibody is available here: https://www.bosterbio.com/msds?sku=M04562.

What is Anti-RBCK1 (UBCE7IP3) Antibody used for?

Boster Bio Anti-RBCK1 (UBCE7IP3) Antibody (Catalog # M04562) . Tested in WB application (s) . This antibody reacts with Human.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.