Anti-KANK1 Antibody

Catalog number M05029-01

Discontinued

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About this product

Boster Bio Anti-KANK1 Antibody (Catalog # M05029) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: M05029-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
Synonyms: KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172
Gene Name: KANK1
UniProt: Q14678
Host: Mouse
Reactivity: Human
Immunogen: This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.
Clonality: Monoclonal
Clone: Clone: 1773CT634.49.61
Tissue Specificity: Widely expressed. Isoform 1 is predominantly expressed in heart and kidney. Isoform 2 probably is widely expressed at basic levels.
Applications: WB, IHC-P
Field of Research: Cancer, Signal Transduction
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Function: 25961457259614572596145725961457
Molecular Weight: 147289 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, k
Subcellular Location: Cell projection, ruffle membrane. Cytoplasm. Nucleus Note=Colocalizes with KIF21A in membrane ruffles (PubMed:19559006) Shuttles between the cytoplasm and nucleus (PubMed:16968744) [Isoform 2]: Cytoplasm. Nucleus Note=Shuttles between the cytoplasm and nucleus

Frequently Asked Questions

What is the catalog number for Anti-KANK1 Antibody?

The catalog number for Anti-KANK1 Antibody is M05029.

Is Anti-KANK1 Antibody in stock?

Anti-KANK1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-KANK1 Antibody?

The safety data sheet for Anti-KANK1 Antibody is available here: https://www.bosterbio.com/msds?sku=M05029.

What is Anti-KANK1 Antibody used for?

Boster Bio Anti-KANK1 Antibody (Catalog # M05029) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.