Anti-PURB Antibody (C-term)

Catalog number M06224-01

Discontinued

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About this product

Boster Bio Anti-PURB Antibody (C-term) (Catalog # M06224) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: M06224-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Synonyms: Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
Gene Name: PURB
UniProt: Q96QR8
Host: Mouse
Reactivity: Human, Mouse
Immunogen: This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.
Clonality: Monoclonal
Clone: Clone: 2117CT1176.48.6
Tissue Specificity: Expressed in myocardium of heart failure patients.
Applications: WB
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution: WB: 1:8000
Function: Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Molecular Weight: 33241 Da
Shipping Conditions: Available
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment: IgG1, κ
Subcellular Location: Nucleus.
Prediction Reactivity: Human, Mouse

Frequently Asked Questions

What is the catalog number for Anti-PURB Antibody (C-term)?

The catalog number for Anti-PURB Antibody (C-term) is M06224.

Is Anti-PURB Antibody (C-term) in stock?

Anti-PURB Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PURB Antibody (C-term)?

The safety data sheet for Anti-PURB Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=M06224.

What is Anti-PURB Antibody (C-term) used for?

Boster Bio Anti-PURB Antibody (C-term) (Catalog # M06224) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.